Medullary Thyroid Carcinoma: Therapy and Management
نویسندگان
چکیده
منابع مشابه
Thyroid: Medullary Carcinoma
Medullary thyroid cancers (MTC) are rare neuroendocrine tumors arising from the parafollicular C-cells of the thyroid. In this review, we provide a general overview of the classification, pathology, and clinical management of MTC. In the latter half, we survey the underlying genetic framework of MTC and its potential implications within a diagnostic and therapeutic context.
متن کاملPediatric Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC), which originates from thyroid parafollicular C cells, accounts for 3 to 5% of thyroid malignancies. MTC occurs either sporadically or in an inherited autosomal dominant manner. Hereditary MTC occurs as a familial MTC or as a part of multiple endocrine neoplasia (MEN) type 2A and B syndromes. A strong genotype-phenotype correlation has been observed between her...
متن کاملMedullary thyroid carcinoma.
OBJECTIVE This review outlines advances in the diagnosis, genetic testing, and progress in medullary thyroid cancer (MTC) treatment in light of the most recent evidence. METHODS English-language articles pertaining to MTC published up to 2012 were reviewed. The pertinent articles and their references were obtained and those considered relevant were reviewed for inclusion. RESULTS MTC is an ...
متن کامل8.1. Diagnosis and Management of Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC) arises from thyroid C cells that secrete calcitonin (CT). It accounts for only about 5% of thyroid carcinomas in the United States (Hundahl 1998), but has aroused considerable interest because of its distinctive biochemical, genetic and clinical features. Although this is usually a sporadic tumor, some are familial tumors that occur as a result of autosomal dom...
متن کاملOncocytic Variant Of Medullary Thyroid Carcinoma - A Case Report
Medullary thyroid carcinoma (MTC) is a rare tumor arising from parafollicular C-cells. The oncocytic variant of MTC is an extremely rare diagnosis, with less than 20 cases reported. Here we present the case of a 36-year-old male patient with complaints of neck swelling and dysphagia. On fine needle aspiration cytology (FNAC), a Hürthle cell neoplasm was suggested. Finally with histopathol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Internal Medicine
سال: 1999
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.38.3